6. Redness of the Palms and Soles
Although more common on the hands, some people with liver disease also develop redness on the soles of the feet, known as palmar or plantar erythema. It’s caused by altered blood flow and hormone levels.
7. Muscle Wasting and Weakness
Advanced liver disease can lead to:
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Thinning of the leg muscles
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Weakness and fatigue
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Difficulty walking or standing for long periods
This happens because the body can’t properly process nutrients and proteins.
When to See a Doctor
You should seek medical advice if leg symptoms appear along with:
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Yellowing of the eyes or skin
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Abdominal swelling
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Chronic fatigue
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Dark urine or pale stools
Early diagnosis can significantly slow disease progression.
Bottom Line
The legs can reveal important clues about liver health. Swelling, skin changes, itching, bruising, and muscle loss should never be ignored — especially if they appear together.